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In Vitro ADME Assays
Rapid 'Design-Make-Test' cycles to help drive your drug discovery programs
Early assessment of absorption, distribution, metabolism, and excretion (ADME) is essential in identifying weaker drug candidates early in the discovery process. This reduces the proportion of compounds failing in clinical trials for ADME reasons.
We offer a comprehensive suite of standard in vitro ADME assays and collaborate with our clients to design purposeful screening cascades tailored to each drug discovery program.
We provide:
- Fast turnaround: A 5-day turnaround for routine Tier 1 assays to accelerate the design-make-test-analyze cycle. Our assays are optimized to minimize compound usage and reduce costs
- State-of-the-art technology: Advanced equipment, automated data management, and expert interpretation by highly experienced scientists ensure high-quality results and rapid decision making, driving your projects forward faster
- High compound throughput: TECAN robotic liquid handling systems provide high compound throughput, reducing variability and accelerating your studies.
- Customized solutions: We recognize that your compounds are unique. Our services are tailored to meet your requirements, providing guidance on best techniques and project management
- Quality assurance: We apply the highest industry standards and strict acceptance criteria, ensuring lean project progression and guaranteed quality service
- Quick quote: Get a precise quote for your ADME project in less than 24 hours by using our ADME calculator.
Take a look at our comprehensive range of standardized in vitro ADME assays:
Physicochemical properties
In vitro metabolism
Protein binding
Permeability and transporters
Drug-drug interaction (DDI)
In vitro toxicology
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Get a precise quote for your ADME project in less than 24 hours by using our ADME calculator.