Chemical Stability

In the intricate dance of drug discovery, the stability of compounds takes center stage, dictating the potential success of a candidate. Compounds susceptible to instability in aqueous environments may struggle to maintain therapeutically effective concentrations in vivo, significantly diminishing their prospects as viable drug candidates. Dosing solutions, a critical avenue, present a battleground where drugs face potential chemical degradation, induced by mechanisms like hydrolysis, oxidation, and light-catalyzed breakdown. The gastrointestinal tract introduces yet another arena for chemical degradation under diverse conditions. Thus, a preemptive understanding of a compound's stability becomes paramount before venturing into animal pharmacokinetic evaluations. Our commitment to precision entails rigorous stability testing in buffer solutions, scrutinizing the compound's resilience at varying pH levels and temperatures. This meticulous approach ensures the early identification of potential weak candidates, steering the course of drug discovery towards robust and promising outcomes within the Concept Life Sciences ethos.