Gene Expression Analysis

DNA/RNA Isolation

Nucleic acids are efficiently purified from a wide range of samples including cells, tissues, liquid biopsies and biofluids, using low, medium or high throughput assay systems. For downstream applications it is critical to reliably quantify nucleic acid yield and purity. We utilize a combination of high accuracy fluorescence based nucleic acid quantification alongside industry standard Agilent® instrumentation for purity analysis.  

Quantitative PCR (RT-qPCR)

In drug discovery, understanding how test biologics or small molecules impact gene expression is a critical to the development pipeline. We will customize our real-time quantitative PCR (RT-qPCR) services to align with your project’s specific needs.

Our highly specific and sensitive RT-qPCR techniques are ideal for confirming and quantifying the expression of drug targets, pharmacodynamic (PD) and predictive biomarkers, supporting a deeper understanding of your compound’s activity and mechanisms of action.

Whether complementing protein expression analysis or addressing gaps in available protein-based targets, RT-qPCR provides powerful insights into the molecular regulation of cellular pathways. Our RT-qPCR services are designed to support standalone studies or more integrated drug discovery projects. whether your samples are generated in-house using our high quality cellular and animal models, or elsewhere, we offer tailored solutions to match your needs.

Multiplex RT-qPCR

Multiplex RT-qPCR enables simultaneous detection of up to four targets in a single reaction and is ideal for studies where cell numbers are limited. This approach maximizes data output while remaining cost-effective and efficient.

Cell-To-CT

Accelerate your workflow with direct-from-cell gene expression analysis—no RNA purification required. Cell-to-CT is the solution for high-throughput screening in cell-based studies and is compatible with both 96- and 384-well plate formats, minimizing turnaround and reducing overall costs.