Comprehensive range of standardized in vitro ADMET assays
Focusing research efforts on compounds that have the best chance of success delivers significant cost and time savings and ensures that safety and efficacy are integrated from the outset. Identifying the compounds to discard is nearly as important as choosing the ones to progress. Early assessment of absorption, distribution, metabolism, excretion, and toxicity (ADMET) is essential in identifying weaker drug candidates early in the drug-discovery process and decreasing the proportion of compounds failing in clinical trials for ADMET reasons.
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