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Empowering Drug Hunters with High-Throughput Protein Crystallography

Abstract:

This webinar explores how high-throughput protein crystallography accelerates hit generation in early drug discovery. Featuring insights from Accelero BioStructures, it highlights the evolution of structural biology and the impact of advanced platforms like ABS-OneStep. Learn how innovative X-ray solutions and strategic partnerships are revolutionizing the identification of viable drug candidates.

Learning objectives:

  • Protein crystallography and its importance in drug discovery.
  • Challenges in crystallography, structural biology and gene-to-structure for drug discovery and protein engineering.
  • Significance of our high-throughput crystallography for drug discovery.
  • Hit generation in drug discovery with our crystallography-based library screening.
  • Interfacing crystallography with biophysics, medicinal and computational chemistry, biology and our AI in drug discovery.

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Dr Debanu Das | CEO and Co Founder | Accelero Biostructures

Debanu has over 20 years of experience in high-throughput protein X-ray crystallography, structure-and fragment-based drug discovery and structural biology. His expertise includes structure-function analysis of a broad range of proteins and drug targets (kinases, proteases, antibody-antigen complexes, nuclear receptors, ubiquitin ligases, methylases, polymerases, microbiome enzymes, membrane proteins, transcription factors).

Dr. Tom Pesnot | Drug Discovery Services Director | Concept Life Sciences

Tom joined Concept Life Sciences in 2017. He has over 15 years’ experience of leading drug discovery programmes in the academic, biotech, and CRO sectors, and contributed to the development of multiple clinical candidates and marketed drugs. His scientific expertise spans a wide range of therapeutic areas (oncology, immuno-oncology, fibrosis and neurosciences) and target classes (kinases, enzymes, GPCRs, ion channels) at all stages of the drug discovery process. A Fellow of the Royal Society of Chemistry, Thomas has authored over 35 publications, reviews, and patents in the field of drug discovery, synthetic chemistry, and enzymology.