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Advancing Macrophage-Targeted Therapeutics: Innovations in Discovery, Modeling, and AI-Driven Analysis

Abstract:

This presentation delves into advanced strategies for macrophage-targeted cancer therapies. Dr. Justyna Rzepecka highlights the development of innovative in vitro human macrophage models to overcome limitations of preclinical studies. These models, derived from healthy donors, accurately mimic patient scenarios, enabling improved target validation and compound screening for more effective anti-cancer treatments. In this webinar we will explore effective strategies for developing macrophage-targeted therapies.

Learning objectives:

  • Identify new therapeutic targets in macrophages.
  • How to use in vitro macrophage models to reflect diverse disease states, including cancer.
  • Combining transcriptomics and AI/ML analysis to understand macrophage function and treatment potential.
  • Assessing drug efficacy and mechanisms of action using functional macrophage assays.
  • Accessing comprehensive support for macrophage-focused drug discovery and development.

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Justyna Rzepecka | Immunology Associate Director | Concept Life Sciences

Justyna has over 15 years of experience in immunology and cell biology, including more than a decade in drug discovery.

She specializes in building and leading research teams, as well as establishing cellular platforms for target validation, lead selection, compound profiling, and biomarker identification.​