Uniting Biology and Digital Drug Discovery to identify new therapeutic opportunities in neurodegeneration

Download our joint webinar with Delta4, featuring Dr. Elise Malavasi and Dr. Samuel Walters, to explore how the combination of human cell biology and AI-driven insights is accelerating the discovery of novel therapeutics — faster, smarter, and without reliance on animal models.

You’ll learn how we:

• Conducted in-depth functional and transcriptomic profiling of human NRA models.
• Built an adaptive and dynamic model of reactive astrocytes enhanced by omics-informed pathways and real human data.
• Used this model to simulate disease states, screen thousands of compounds in silico, and predict their effect on astrocyte reactivity.
• Selected the top-performing candidates for experimental validation in vitro.