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Immunology

Immunology isn't just vital; it's the backbone of multiple aspects of our physiology. Its complexity demands an in-depth grasp, immune-focused solutions, and insights that bridge research to application. We specialize in tailored solutions and extensive expertise in immune mechanisms and cell biology. Our goal? To empower your decisions across drug discovery and clinical stages with precision and confidence.

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A more in-depth view

Our Specializations:

Advanced Pre-Clinical Models: We are proficient in developing bespoke in vitro models for studying immune interactions (mono- and co-culture studies, 2D and 3D spheroid models, disease modelling using primary immune cells obtained from healthy and disease-bearing donors).

  • Cutting-Edge Instrumentation: Utilizing state-of-the-art tools to unravel detailed mechanisms of action and compound effects.
  • Flow Cytometry Profiling: Phenotyping (cell surface and intracellular) immune cells, assessing activation markers, cytokines, and phospho-proteins.
  • Real-Time Cellular Analysis: Examining cellular behaviour such as proliferation, apoptosis, phagocytosis, and chemotaxis.
  • Molecular Insights: Uncovering compound modes of action via bulk and single-cell RNA sequencing.
  • Biomarker Identification: Applying cell-based assays and secretome analysis for biomarker discovery.
  • Specialized Histology Services: Proficient in identifying cellular targets, confirming expressions, and assessing disease pathology changes post-treatment in various tissues.

Our key technologies enabling your immunology drug discovery program and biomarker identification: