CYP450 inhibition (7 isoform) assay data sheet

Inhibitory potency (IC50) provides invaluable information regarding drug interaction potential. The IC50 of test compound against the seven FDA-recommended CYP450 metabolizing enzymes is determined using specific drug probe substrates. Analysis is by LC-MSMS.

Deliverable: IC50 (μM) of test compound against CYP1A2, CYP2B6, CYP2C8, CYP2C9, CYP2C19, CYP2D6 & CYP3A4 (Midazolam & Testosterone).

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