Oncology
Cancer is a complex, multifaceted disease with an array of traits or “hallmarks” that can be targeted by different therapeutic approaches. Our skilled team has extensive experience supporting companies in characterizing lead compounds through in vitro pharmacology. We're dedicated to delivering both established and customized assays, along with assay development services. Our testing platforms cover diverse 2D and 3D models, incorporating advanced techniques like molecular biology, high-content imaging, and live cell imaging.
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Our techniques
2D Cell Lines:
Access our diverse inventory of cell lines representing various cancers and tissues instantly. We can also source specific cell lines from commercial vendors based on project needs.
3D Spheroid Models:
Transitioning from 2D to 3D cell culture aids in advancing drug development and reduce later clinical stage failure. Explore established 3D models from multiple cancer cell lines, with or without fibroblast co-cultures for tailored 3D structure formation.
Immunotherapy Expertise:
Leverage our immuno-oncology expertise to understand your drug candidates' immunomodulatory effects within the tumour microenvironment. Dive into immunotherapeutic assessments using our 2D and 3D in vitro models co-cultured with non-autologous immune cells.
Advanced Cell Characterization via RNA Seq:
Utilize our 2D and 3D model capabilities, along with bulk or single-cell transcriptomics, for in-depth lead compound characterization or drug repositioning programs.
High-Content Services:
Gain comprehensive insights into complex human biology through powerful 2D and 3D in vitro imaging-based assays on our high-throughput imaging platform.
Live Cell Analysis:
Track real-time morphological and phenotypic changes for pathway and mechanistic studies. Our system facilitates continuous monitoring of cell proliferation, apoptosis, and migration in both 2D and 3D spheroid models.
