Estrogen Receptor Assay, Test No 455

In the realm of cutting-edge research, Concept Life Sciences leverages the VM7Luc4E2 cell line—an instrumental entity expressing both Estrogen Receptors α and β (ER α and β). This cell line, fortified by stable transfection with an ER-responsive luciferase reporter gene, emerges as a powerful tool in discerning chemicals' impact on ER-dependent transcription, differentiating between agonists and antagonists. Our VM7Luc4E2 Estrogen Receptor Transactivation Assay (ERTA) aligns seamlessly with OECD Guidelines for the Testing of Chemicals, Test No. 455, operating in both agonism and antagonism modes. This meticulous approach, coupled with a diligent check on cell viability, ensures the accuracy and reliability of our results, laying a robust foundation for the interpretation of data. Concept Life Sciences pioneers advancements in ER-related research, delivering insights crucial for drug development and regulatory compliance with clarity and precision.