Aromatase (CYP919) Assay

Within the realms of meticulous research, Concept Life Sciences harnesses the power of the aromatase (CYP19) assay, employing human recombinant CYP19 microsomes. This sophisticated assay meticulously gauges CYP19 activity through a radiometric method, precisely measuring the release of [3H]-H2O from 1β-[3H]-androstenedione catalyzed by CYP19. Aromatase, a key player in estrogen biosynthesis, intricately converts androgens like testosterone and androstenedione into vital estrogens—estradiol and estrone. This method, aligned with OCSPP 890.1200 standards, stands as a beacon in Concept Life Sciences' arsenal, offering nuanced insights into the dynamic world of CYP19 activity. With scientific precision, we navigate the complexities of estrogen biosynthesis, providing clarity that extends the frontiers of research and contributes significantly to drug development and regulatory compliance