The AR-EcoScreen™ cell line expresses the human androgen receptor (AR) and has been stably transfected with an AR-responsive luciferase reporter gene to identify chemicals that activate (agonist) or inhibit (antagonist) AR-dependent transcription.
The AR-EcoScreen™ Androgen Receptor Transactivation Assay (ARTA) is performed in agonism and/or antagonism mode, based on the OECD Guidelines for the Testing of Chemicals, Test No. 458. Cell viability is checked to enable accurate interpretation of results.
Deliverable: A Study Report will be provided in draft for customers’ comments, prior to report finalization.
