Separation Sciences
Separation Sciences - Bioanalysis
Synthetic Chemistry - Selected
Physical Characterisation – Size and Shape
Physical Characterisation
Physical Characterisation – Biophysical Analysis
Elemental, Raw Materials, Other
Pre-Formulation / Formulation / Sample Prep
Separation Sciences
Vendor |
Description |
Model |
GMP / GLP |
Thermo Scientific |
uHPLC – PDA |
Ultimate 3000 |
✔ |
uHPLC – Refractive Index |
Ultimate 3000 |
✔ |
uHPLC – Fluorescence |
Ultimate 3000 |
✔ |
uHPLC – CAD |
Ultimate 3000 |
✔ |
uHPLC – Electrochemical |
Ultimate 3000 |
✔ |
uHPLC – UV/MS/MS |
Vanquish PDA + Altis TSQ |
✔ |
uHPLC – UV/MS/MS |
Vanquish PDA + Fortis TSQ |
✔ |
uHPLC – UV/MS/MS |
Vanquish PDA + iSQ |
✔ |
Waters |
HPLC – PDA |
Alliance 2695 |
✔ |
HPLC – ELS/D x 2 |
Alliance 2695 |
✔ |
HPLC – Refractive Index |
Alliance 2695 |
✔ |
Perkin Elmer |
GC – FID (Head space & Liquid injection) |
Autosystem XL |
GMP |
GC – FID (Head space & Liquid injection) |
Clarus 400 |
GMP |
GC – FID (Liquid injection) |
Trace 1310 |
✔ |
GC – FID and MS (Liquid injection) |
Trace 1310 with iSQ |
✔ |
GC – FID and MS/MS (Head space & Liquid injection plus SPME) |
Evo 8000 with TSQ, TriPlus Autosampler |
✔ |
Metromh |
Ion Chromatography – CD, PAD, Conductivity, Cations |
940 Pro with HPG |
✔ |
Malvern Panalytical |
Chromatography – SEC / GPC |
OmniSEC Reveal & Resolve: UV, Viscosity, RI & LALS2 |
✔ |
Separation Sciences - Bioanalysis
Vendor |
Description |
Type |
GMP / GLP |
Agilent |
GC – FID and MS (Head space & Liquid injection) |
5977A |
GLP |
Sciex |
uHPLC-MS/MS |
6500 |
GLP |
2D-uHPLC-MS/MS (MRM and MRM³) |
6500 QTrap® |
GLP |
2D-uHPLC-MS/MS (MRM and MRM³) + SelexION |
6500 QTrap® |
GLP |
Thermo Scientific |
uHPLC – UV/Vis (3D data acquisition capability) |
Vanquish Flex |
GLP |
Waters |
uHPLC – PDA (liquid cell RAD detectors across D2C) |
Acquity Arc |
Non-GXP |
Synthetic Chemistry - Selected
Vendor |
Description |
Vendor |
Description |
Agilent |
7890 HS-GC/MSD |
Jeol |
NMR ECX-300 MHz |
GC-MS/MS-FID (various) |
NMR ECX-400 MHz |
LC-MS/MS (various) |
NMR ECZ-400 MHz (GMP) |
1100 GPC |
Schimadzu |
uHPLC / SFC with PAD & MS |
Bruker |
NMR Advance III HD 400 MHz |
Waters |
AutoPurification HPLC / MS for Mass-directed impurity isolation |
Physical Characterisation – Size and Shape
Vendor |
Description |
Model |
GMP / GLP |
Malvern Panalytical |
Particle Size & Counting – Resonant Mass |
Archimedes |
GMP |
Particle Size Analysis – Laser Diffraction |
Mastersizer 3000 x 2: Hydro SV, Hydro MV, Hydro EV & Aero S |
✔ |
Particle Size Analysis – Laser Diffraction |
Mastersizer 2000: Hydro SM, Hydro S & Sirocco |
GMP |
Particle Size, Shape, Optical & Raman Microscopy, MDRS |
Morphologi4 ID x 5 |
✔ |
Spray Analysis – Nasal, DPI, MDI, Aerosols |
Spraytec |
✔ |
Particle Size Analysis, DLS & Zeta Potential |
Zetasizer Ultra Red |
✔ |
Nanoparticle Tracking & Counting |
NanoSight NS3000 |
✔ |
Microtrac |
Particle Size Analysis – Laser Diffraction |
S3500 with ASVR & USVR Wet Dispersers |
✔ |
Particle Measuring Systems |
Particle Counting USP <788> & USP <729> |
APSS 2000 |
✔ |
Particle Size Analysis – Laser Diffraction, Dry Powder & Suspension |
HELOS KF Vario / RODOS T4.1 with VIBRI & ASPIROS Dosing |
✔ |
Sympatec |
Particle Size Analysis – Laser Diffraction, Dry Powder & Suspension |
HELOS BR / RODOS L with VIBRI & ASPIROS Dosing |
✔ |
Physical Characterisation
Vendor |
Description |
Model |
GMP / GLP |
Bruker |
X-Ray Diffraction |
D8 Advance, with LynxEye Detector |
GMP |
Jasco |
Fourier Transform Infrared Spectroscopy |
FT/IR-4600 CFR with ATR, KBr Disc, Liquid, Nujol Mull |
✔ |
Malvern Panalytical |
X-Ray Diffraction |
Empyrean S3, High Throughput & Environmental Stage |
✔ |
Malvern Panalytical |
X-Ray Diffraction |
Aeris Research Edition |
✔ |
Micromeritics |
Porosity and Specific Surface Area Analysis (BET SSA) |
TriStar 3000 and TriStar II 3020 FlowPrep 060 (x 3) |
GMP |
Perkin Elmer |
Differential Scanning Calorimetry |
DSC 8000: mDSC, Hyper DSC |
✔ |
Perkin Elmer |
Thermogravimetric Analysis |
TGA 8000 |
✔ |
SMS |
Dynamic Vapour Sorption, Water |
Discovery Aqua |
✔ |
TA Instruments |
Isothermal Calorimetry |
TAM III: RH Perfusion & Nano Calorimeters |
GMP |
Netsch |
Rheometry |
Kinexus Ultra+ |
GMP |
Physical Characterisation – Biophysical Analysis
Vendor |
Description |
Model |
GMP / GLP |
Creoptix |
Grated-Coupled Interferometry (GCI) |
Creoptix WAVEdelta |
Non-GXP |
Cytiva |
Surface Plasmon Resonance (SPR) |
Biocore T200 |
Non-GXP |
Cytiva |
Surface Plasmon Resonance (SPR) |
Biocore 8k |
Non-GXP |
Malvern Panalytical |
Chromatography – SEC / GPC |
OmniSEC Reveal & Resolve: UV, Viscosity, RI & LALS |
Non-GXP |
Malvern Panalytical |
Microcalorimetry – Differential Scanning Calorimetry |
MicroCAL PEAQ-DSC Automated |
Non-GXP |
Malvern Panalytical |
Microcalorimetry – Isothermal Titration Calorimetry |
MicroCAL PEAQ-ITC |
Non-GXP |
Malvern Panalytical |
Microcalorimetry – Isothermal Titration Calorimetry |
MicroCAL PEAQ-ITC Automated |
Non-GXP |
Malvern Panalytical |
Nanoparticle Tracking & Counting |
NanoSight NS3000 |
Non-GXP |
Malvern Panalytical |
Particle Size Analysis, DLS & Zeta Potential |
Zetasizer Ultra |
Non-GXP |
Elemental, Raw Materials, Other
Vendor |
Description |
Model |
GMP / GLP |
Agilent |
ICP-MS |
7900 Single Quadrupole MS |
✔ |
Endecotts |
Sieve Shaker |
Octagon-200 |
✔ |
Erweka |
Dissolution Testing |
DT800 HH (8 bath) |
✔ |
Erweka |
USP Bulk / Tapped Volumetry |
SMV102 |
✔ |
FEI |
SEM & SEM-EDX |
Quanta 400 E-SEM |
Non-GXP |
Gilson |
Ultrasonic Sifter |
GilSonic AutoSiever |
✔ |
Perkin Elmer |
UV Spectrophotometry |
Lambda 365 |
✔ |
Hach Lange |
UV Spectrophotometry |
DR3900 / LT200 Heater |
✔ |
Metromh |
Autotitration |
904 Titrando & 716 DMS Titrino |
✔ |
Metromh |
Karl Fischer – Coulometric / Volumetric |
852 Combined Karl Fischer with 860 Oven & 701 KF Titrino |
✔ |
Mettler Toledo |
Moisture Balance |
HR83-P x2 |
✔ |
Suez |
Total Organic Carbon |
Sievers 900 |
GMP |
Thermo Scientific |
ICP-OES |
iCAP 6500 Duo |
✔ |
Torsion Balance Supplies |
Torsion Balance |
OS Torsion Balance |
✔ |
Pre-Formulation / Formulation / Sample Prep
Vendor | Description | Model |
---|
Copley Scientific | Next Generation Impactor | NGI with Quartz Discs & Cups |
Erweka | Disintegration Tester | ZT 221 |
Food Pharma Systems | Microniser | Pilot Mill 2 |
Fritsch | Nanomill (4 position) | Pulverisette 5 |
Heidolph | Heater Shaker / Cycling Incubator | Titramax 1000 |
Knauer | Osmometer | K-7400S |
Leica | Benchtop Optical Microscope | DMLS |
Metromh | pH Stat Titrator | Titrando 902 |
Memmert | Stability Incubators, 260L | HPP260 x 3 |
Source Bioscience | Stability Chambers, 3000L | 5902-TS x 2 |
Spex | Ball Mixer / Mill | 8000M |
Technobis Crystallisation Systems | Multi-reactor crystalliser (16 x 1 mL) | Crystal 16 v3 |
Turbula | Tumble Blender (2 Litre Pail) | T2F |
TECHNE | Sample Concentrator | FSC400D x 2 |
Additional Equipment:
- Silverston mixers
- Overhead stirrers
- Vortex mixers
- Hotplates
- Bottle rollers
- Wrist shakers
- Centrifuges
- Glove box
- Vacuum ovens
- Chamber furnace
- Rotary evaporator
- Melting point
- Analytical & Specialist balances
- pH & Conductivity meters
- Deionised water systems
- Distilled water system.