Pharmaceutical chemistry

Concept Life Sciences has one of the largest, most skilled and experienced chemistry groups in the UK. We have over 25 years’ experience in the synthesis of novel organic compounds with the majority of our chemists educated to PhD level.

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A comprehensive range of synthesis services

Concept provides a comprehensive range of synthesis services to the pharmaceutical industry and academic life science sectors and can design and expedite routes to even the most challenging of targets.

We offer milligram to kilogram chemistry synthesis for APIs, intermediates, reference compounds, focused libraries, stable isotopically labelled compounds, competitor compounds, scaffolds, building blocks, analogues, drug metabolites and impurities.

We have supported and driven projects in these areas for a variety of clients that include world leading academic institutions, virtual start-ups, globally renowned organisations and international research bodies.

Our synthetic expertise is supported by a wealth of analytical instrumentation that are either open access or run by a dedicated team of analytical chemists.

Service, technologies & capabilities

  • Nanoparticle chemistry
  • Metabolite synthesis
  • Green chemistry
  • High pressure chemistry up to 7.8L (including hydrogenation and carbonylation)
  • Flow chemistry
  • Photoredox chemistry
  • Ozonolysis
  • Scale-up chemistry
  • Microwave assisted synthesis
  • Prep HPLC
  • Automated purification
  • NMR
  • HPLC-MS
  • GCMS
  • LCMS
  • Counter current chromatography
  • IR
  • DSC
  • Chiral LC
  • SFC
  • GPC

Latest equipment and methodologies

Concept’s highly trained chemists use their knowledge and the latest equipment and methodologies to explore new chemical space, adding value to client projects through the generation of intellectual property. Our chemists have been named as co-authors on numerous patents and publications and we have been included in numerous finals of the RSC/SCI National Retrosynthesis Competition.