Investigating the Characteristics of Packaging Films

Summary

Having previously worked on other projects with them, Agenda1 were selected by the client to assist with two different investigations of issues relating to their high end packaging film products. The investigations used both in house equipment and experienced analysts as well as carefully selected and guided independent suppliers.

Background

The client is a fast growing established innovative manufacturer who provides packaging for a range of products to many national and international companies. Food packaging products and cigarette packaging films are two of their many products.  In one piece of work Agenda1 were selected to develop an analytical method to investigate whether a product had any residual organic solvents which might taint the packaged product. This work required careful planning as only a limited amount of material was available and the level to which potential contamination might exist was very low. The potential contamination issue was investigated using Head Space GC equipment and an Agenda 1 specific method, and later involved guidance of, and collaboration with a University team.

In a second piece of work the client wanted was to determine the levels of crystallinity in their packaging material as this affects the transparency of the film, a critical feature when selling the material. For this work Agenda1 developed a client specific XRD method using their in house equipment, with part of the work including a day of joint work with the client on site. This measurement of film packaging was quite atypical but the team rose to the challenge.

Resources

Agenda1 have a skilled team of scientists operating a wide range of in house GMP compliant equipment. Previous experience developing methods for crystallinity determination guided the film crystalinity work, utilising a Bruker-AXS D8 Advance X-Ray Diffractometer. The residual solvent task utilised a proprietary 18 month, grant funded HS-GC method with work carried out on a  PerkinElmer HS40 HS-GC.

Application

This example demonstrates the ability of Agenda1 to quickly develop client specific methods to help solve very particular client challenges. The XRD method development included addressing the difficulties which arose when mounting unusual samples into the instrument.

Results

In both studies the client was provided with a definitive report outlining the nature of the issue, the techniques and resources used to investigate it, and a report giving conclusions.  For the HS-GC analysis a formal certificate of analysis was provided.