Metabolites and standards

Concept Life Sciences’ highly skilled chemists are able to quickly produce complex analytical standards, metabolites and impurities as required for testing across a number of sectors. This synthetic expertise is supported by extensive cutting-edge analytical instrumentation from our dedicated analytical scientists.

Complex chemical synthesis

Over 85% of our dedicated chemists are educated to PhD level, have diverse industrial experience and excel in problem solving and synthesising difficult to access compounds. With decades of experience within the group, they have worked on multiple FTE programmes for global R&D organisations. You can rely on our highly trained scientists to overcome your complex challenges and lead you to success.

Our superb facilities and technical equipment capabilities enable us to handle complex or urgent projects with ease. We pride ourselves on high quality, transparency and data integrity to offer you true expertise and collaboration.

We routinely devise novel routes to produce difficult to access compounds and are able to synthesise stable isotopically labelled (SIL) compounds. We typically handle 2H, 13C and 15N but can also incorporate 18O. When designing a synthesis we take into account lability, the most appropriate time to introduce the label(s) and the location of label(s) [for metabolic or mechanistic studies].

Complex chemical entities that can be used as analytical reference compounds, metabolites or impurity profiling, can be synthesised to your specification, typically at high purity, using the latest innovative methodologies and specialist equipment.

With specialised expertise, purification and analytical support these molecules could be natural products, contain numerous chiral centres or, as we possess the required licenses, controlled substances.

Analytical services
  • SFC
  • NMR
  • HPLC-MS
  • GCMS
  • Counter current chromatography
  • IR
  • DSC
  • Chiral LC
  • Prep HPLC
  • Automated purification
Chemical Capabilities
  • Chiral synthesis
  • Stable isotopically labelled synthesis (SIL)
  • Photoredox chemistry
  • High pressure chemistry (including hydrogenation and carbonylation)
  • Flow Chemistry

You might also be interested in...

Chemistry

We offer milligram to kilogram chemistry synthesis for APIs, intermediates, reference compounds, focused libraries, stable isotopically labelled compounds, competitor compounds, scaffolds, building blocks, analogues, drug metabolites and impurities.

Toxicology

Concept Life Sciences is a leading provider of predictive, mechanistic and investigative pharmacology and toxicology solutions to the chemical, agrochemical, cosmetics and consumer product industries.

Analytical

Our unique blend of spectroscopic, chromatographic, solid state, elemental and compendial test methods provides comprehensive analytical solutions from product characterisation and registration through to commercial release testing.