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Scientist – In vitro Toxicology and Bioanalysis

The company offers a wide range of specialist contract research services. This position is focussed on delivering a diverse range of in vitro assays to regulatory standards, for the purpose of defining safety parameters as required by the Agrochemical and Pharmaceutical industry.

We are looking for an experienced in vitro scientist with a sound knowledge of chromatographic and mass spectrometric techniques for our GLP in vitro toxicology and endocrine disruptor assay services at our site in Dundee. The ideal candidate will be able to demonstrate a sound knowledge of in vitro assay development and bioanalytical readouts and will have gained previous experience working to regulatory standards in a CRO or industry setting.

General responsibilities

  • Develop chromatographic methods (LC-MS, LC-MS/MS) for support of bioanalytical and toxicology studies
  • Analysis, collation and interpretation of data
  • Record, file and archive data in accordance with appropriate SOPs
  • Understand regulatory requirements for the work being conducted (GLP and GCP) where required and strive for excellence in terms of accountability, record keeping, and quality of output
  • Preparation of standard reagents and compounds as required
  • Validation and optimization of new in vitro assay and bioanalytical methods
  • Implementing quality control steps to ensure projects are conducted and delivered according to the standards expected, including developing new or updating SOP’s as required
  • Assist the preparation of Study Plans and Reports in standard or customer-required format
  • Actively interrogate scientific literature to understand relevant advances in the field of Endocrine disruption and associated disciplines as necessary for individual projects
  • Planning of projects in advance, arranging resources required for experimental conduct, ordering reagents and other laboratory maintenance tasks
  • Accurate record keeping of all experimental work, from initial protocol development, laboratory notes, to write up of results and report production

Qualifications/Skills/Experience

  • Life science degree (Cell Biology or related disciplines) essential, MSc advantageous, ideally with at least 2 years’ experience in a CRO or industry setting working to regulatory standards.
  • Proven chromatographic and mass spectrometric techniques
  • Proven experience of working to GLP for in vitro services
  • Experience in method development and validation to OECD guidelines highly advantageous
  • Experience of enzymatic and cell-based assays highly advantageous
  • High-level attention to detail and organisational skills
  • Excellent data analysis and interpretation skills
  • Proven experience in using Microsoft Excel and GraphPad Prism
  • Excellent team player
  • Strong verbal communication skills, participating in lab and client discussions

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