Non GLP safety assessment and pre-candidate profiling

We can provide in vitro safety pharmacology assessment of cardiac and neuronal ion channels on automatic and manual patch and multi-electrode array. We carry out in vitro phenotypic assays for cardiac and neuronal toxicity, as well as cytotoxicity and genotoxicity assessments.

Other services include:
  • DDI and metabolic profiling
  • General and investigative toxicity (non GLP)
  • Pathology and histopathology
  • Integrated risk assessment
  • Toxicokinetics and dose prediction
  • Synthetic pathway optimisation and impurity assessment
  • Developability assessment (polymorph and crystalline form assessment)
  • Aerosol and particle size analysis