We have an in-depth knowledge of agrochemical exploratory toxicology, having supported the programmes of leading agrochemical companies for many years. We can run individual studies or support entire programmes. A typical exploratory toxicology programme will have two to four key components.
- First-in-animal acute toxicology studies
- Repeat dose 7, 14, or 28 day studies, potentially with mechanistic endpoints
- If the biological target warrants it, mechanistic in vitro screens for potential mechanisms of concern
- Cross-species in vitro metabolism