Overview

Our business offers a comprehensive range of services to clients in the pharmaceutical, biotechnology, agrochemical, petrochemical, chemical and consumer products industries.

We can collaborate across all areas of your discovery and development programme as you progress from first concept to the launch of a finished product. Our highly trained scientists will provide support every step of the way from target to lead, lead to candidate and candidate to development.

Our scientists are experienced in complex chemistry (synthesis), pharmacology and pathways analysis. By ensuring our medicinal chemists, our computational chemistry team, our synthetic chemistry and in vitro ADMET departments are always working in step with each other we can accelerate the testing cycle.

Trust us to solve issues relating to the safety of compounds or selection of research candidates. We are experts in investigative and mechanistic toxicology, exploratory and discovery toxicology, PK and metabolism and dermal absorption.

We offer over 35 different analytical techniques, including specialist materials characterisation instrumentation, chromatography and formulation/salt/polymorph screening. Where required our services are cGMP certified.

Sectors

With our range of services to support drug discovery and development from first concept to the clinic door, we specialise in delivering difficult projects to challenging timelines.
Our expertise in synthetic chemistry, mechanistic toxicology and in vitro dermal absorption plays a key role in supporting the development of new products for the personal care and cosmetic markets.
We provide chemical design & synthesis, scale up, exploratory toxicology, investigative toxicology, in vitro dermal absorption and analytical services to the agrochemical industry.
Our expertise in synthetic chemistry, mechanistic toxicology and metabolism and adsorption is used by the specialty and petrochemical industries as well as emerging hi-tech industries such as printable electronics, diagnostics and nanotechnology.

Our Discovery & Development team

We have an outstanding executive team with a proven track record. Our people have many years experience in the industry. Many of them are leading scientists with long and distinguished careers in their chosen field of expertise.

Operational Leadership

Dr Paul Doyle
Chief Operating Officer Peakdale Molecular
Doyle
A career spent working at the interface of chemistry and biology means our Chief Operating Officer is committed to serving the cutting edge of drug discovery. Paul holds a degree in chemistry from New College, Oxford and achieved his D.Phil. at the University of Sussex. He has previously been Secretary to the UK Peptide and Protein Group and was one of the instigators of the BioMolecular Structure Unit at the University of Sussex. Paul is a Fellow of the Royal Society of Chemistry (FRSC).
Supported by:
Gordon WoodrowHead of Sales & Marketing
Dr Dave LeeseHead of Chemistry (Chapel)
Dr Paul BradleyHead of Chemistry (Sandwich)
Dr Christopher DoeHead of Biology
Ian Siragher
Managing Director Agenda1
Siragher
Ian has an in-depth understanding of analytical services and new drug development for the pharmaceutical and biotechnology industries. He has a proven track record in growing a specialist contract research and analytical services business focused on the healthcare and medical devices industries.
Supported by:
Dr Simon BristowTechnical Director

Scientific Leadership

Dr Paul Doyle
Chief Scientific Officer Chemistry: Discovery & Development Services
Doyle
A career spent working at the interface of chemistry and biology means our Chief Operating Officer is committed to serving the cutting edge of drug discovery. Paul holds a degree in chemistry from New College, Oxford and achieved his D.Phil. at the University of Sussex. He has previously been Secretary to the UK Peptide and Protein Group and was one of the instigators of the BioMolecular Structure Unit at the University of Sussex. Paul is a Fellow of the Royal Society of Chemistry (FRSC).
Supported by a senior scientific team that includes:
Dr Dave LeeseHead of Chemistry
Dr Paul BradleyHead of Chemistry
Dr Christopher DoeHead of Biology
Dr David FengasResearch Leader
Dr Mark BetsonResearch Leader
Dr Paul BlaneyResearch Leader
Dr Bruce LeslieResearch Leader
Dr Dave DawkinsResearch Leader
ANTHONY HUXLEYResearch Leader
Dr Simon Bristow
Technical Director
simon
Simon has a proven track record in delivering specialist analytical services to support early stage drug development programmes. His focus is not only on introducing new technologies and managing our laboratory work flows within a quality compliant environment but also forging long lasting relationships with clients and suppliers. During an impressive and distinguished career, Simon has overseen a wide range of specialist analytical activities covering both research and development and GMP manufacturing. He has worked on numerous publications.
Supported by a senior scientific team that includes:
Dr Eleanor HurstChromatography Manager
Dr Caroline GermanDirector of Site Operation